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Co-administration of an OCT2 inhibitor, cimetidine (300 mg four times daily), with varenicline (2 mg single dose) to 12 smokers increased the systemic exposure of varenicline by 29% (90% CI: 21.

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The effect of smoking cessation counselling in pregnant women: a meta-analysis of randomised controlled trials.

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The USPSTF revised the recommendation to include a table that highlights effective components of behavioral interventions and provided links to additional resources on pharmacotherapy options and resources for pregnant women.

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Effective behavioral interventions provided more intensive counseling than minimal advice and other standard components of usual care ().

If the number of registrants requesting to speak is greater than can be reasonably accommodated during the scheduled open public hearing session, FDA may conduct a lottery to determine the speakers for the scheduled open public hearing session.

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Most patients with smoking-related cancer appear motivated to quit smoking at the time of diagnosis.

Concurrently, a short-acting beta2 agonist, such as albuterol, is usually prescribed as a rescue drug.

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Additional research is also needed on interventions for light or nondaily smokers and to better understand the effectiveness of newer technology platforms for interventions for smoking cessation, such as Internet-based programs, mobile or smartphone applications, and text-messaging programs.

This article reviews literature regarding safety of smoking-cessation aid varenicline for patients with mental illness.

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Varenicline is pharmacologically known as an alpha4beta2 nicotinic acetylcholine receptor partial agonist, which means that it activates the brain's nicotinic receptors in a manner similar to nicotine, but with less affinity (effect).

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